Could This Be the Reason Your Reactive Dog Is Still Struggling?

Last Updated: 30 March 2026
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You’ve read the books. Hired the trainers. Tried the techniques. Yet, every walk still feels like a high-stakes mission. Your dog lunges at other dogs, barks uncontrollably at strangers, or shuts down at the slightest trigger. If you feel like you’ve tried everything to help your reactive dog, read this; it could be the missing piece you haven’t considered.

Author: Anna Bain

Expert Contributor: Dr Katie Woodley

Could This Be the Reason Your Reactive Dog Is Still Struggling?

Contents

Blog in 60 Seconds
Who we are & why this matters
A new perspective on reactivity in dogs
My experience: knowing training wasn't enough
Bringing nutrition, training & behaviour together
The physiology of reactive dogs
Why this matters
The science behind food and behaviour
How diet impacts dog reactivity
The hidden stressors in processed diets
The hormonal impact of poor diets on reactive dogs
The best dog food for reactive dogs
The king of calm: GABA
Supplements that support a reactive dog
Ready-made dog supplements
Reactive dog nutrition
Reactive Dog Nutrition FAQs
References

Blog in 60 Seconds

In this guide, you will learn:

Why reactivity in dogs is as much a biological issue as a behavioural one — and what that means for how you approach it
How the gut-brain axis directly influences your dog’s stress responses, emotional regulation, and ability to recover from triggers
Why ultra-processed dog food can make reactivity worse through blood sugar spikes, gut dysbiosis, chronic inflammation, and nutrient depletion
Which key nutrients and natural herbs support a calmer nervous system, including how GABA, omega-3s, and adaptogens play a role
How a fresh, species-appropriate diet lays the foundation for emotional balance, and which targeted supplements can provide additional support for reactive dogs

You’ve probably Googled things like:

“How can I stop my dog lunging at dogs on walks?” “Why is my dog reactive to everything?” “How do I calm my anxious dog?”

And many of the answer points to training, desensitisation, and management strategies.

But your dog’s behaviour isn’t only about training; what’s going on inside their body is just as important.

Yes, reactivity is a biological issue as much as a behavioural one. And nutrition plays a huge role in how your dog experiences stress, fear, and emotional balance.

Who we are & why this matters

I’m Anna Bain, an accredited canine nutritionist and writer for ProDog Raw. My journey with Rudi opened my eyes to the complexities of reactive dogs and deepened my understanding of the power of nutrition in cultivating calm. Supporting him helped me lean into my knowledge of natural, real food and develop a more in-depth approach to how diet influences behaviour.

Dr. Katie Woodley is a holistic veterinarian with a clinical background in integrative medicine. She specialises in bridging the gap between conventional veterinary care and natural, nutrition-based healing through her website and online community at The Natural Pet Doctor.

Together, we’re here to give you the full picture—the science, the real-world understanding, and the practical steps to help your reactive dog feel calmer, happier, and more confident.

A new perspective on reactivity in dogs

Living with a reactive dog is an emotional rollercoaster—frustrating, overwhelming, and exhausting.

Perhaps you’ve put in the work. You’ve studied behaviour techniques, followed training plans, and tried to desensitise your dog to their triggers. Yet the lunging, barking, and stress-filled reactions persist.

So what’s missing?

What if I told you that dog anxiety and diet are deeply connected? That your dog’s ability to stay calm and process stress isn’t just about training, lifestyle changes or how your respond to them, but also about their gut health and what’s in their bowl.

My experience: knowing training wasn't enough

When I brought Rudi home, I knew rehoming a 13-month-old Northern Inuit wouldn’t be plain sailing. I expected challenges, but I didn’t expect just how much his reactivity would impact our lives.

The first few days? Seemed fine. But once he settled in, it was like a switch flipped. He became overstimulated and overwhelmed; his emotions took the wheel. His extreme reactivity bursting to the surface.

At the time, I had no clue what was really going on. All I knew was that I had a big dog with big reactions, and his behaviour felt chaotic, destructive, and completely out of control.

Walks felt unpredictable. He’d lunge at other dogs, certain people and bikes. His world felt overwhelming to him, and in turn, the situation became overwhelming for me.

At first, I did what most owners do. I threw myself into behaviour modification and training. I worked to build Rudi’s confidence, understand his triggers, and create a world where he felt safer. But it wasn’t just about his behaviour. I had to look at my own reactions too. How I responded to him at home and out in the world mattered just as much. Because it all links.

And while training was crucial, so was what was happening inside his body. That’s when I leaned into what I already knew: mood, behaviour, and diet are all connected. So, alongside training, I refined his nutrition, focused on balancing his gut health, and ensured he had the right calming diet to support his nervous system.

Bringing nutrition, training & behaviour together

But here’s where the gap often lies:

Training teaches a dog what to do.

Nutrition supports their ability to do it.

Let’s be clear—behaviour support and training are essential. If you’re struggling with a reactive dog, professional guidance to help manage escalations and implement behaviour strategies is crucial.

What Is a Reactive Dog? Understanding the Real Causes (And What You Can Do About It)

Understanding reactivity in dogs

Reactivity isn’t just about the outward behaviour, whether that’s barking, lunging, freezing, all three, or something entirely different—it’s about how your dog processes the world. It’s easy to mistake it for aggression in some instances, but reactivity is usually driven by fear, frustration, or emotional overload.

Some dogs react because they’re scared, overstimulated, stuck in a habit, or simply haven’t learned how to cope with their environment – and that’s just a few of the possible reasons. While each dog’s triggers are unique, the root issue is often the same: they’re struggling to regulate their emotions.

The physiology of reactive dogs

Vet insights from Dr. Katie Woodley :

“Most people approach reactivity as purely a behavioural problem, but the reality is, it’s deeply tied to physiology and internal health. A dog’s ability to stay calm, process stress, and recover from triggers depends on a delicate balance of hormones, neurotransmitters, and nervous system regulation.

Reactive behaviours in dogs are often rooted in a complex interplay of physiological processes. At the core, stress and anxiety can trigger a cascade of hormonal and neurochemical changes in your dog’s body. Here are some key factors:

Adrenaline and cortisol overload – When a dog perceives a threat, their adrenal glands release adrenaline and cortisol, preparing the body for a fight-or-flight response. While essential for survival, chronic elevation of these stress hormones leads to heightened reactivity, anxiety, and difficulty calming down. This is why a calming diet for reactive dogs can be crucial in reducing stress responses.

Nervous system imbalance – The autonomic nervous system (ANS) controls involuntary bodily functions and is divided into the sympathetic (fight-or-flight) and parasympathetic (rest-and-digest) systems. Reactive dogs often have an overactive sympathetic response, making it hard to regulate their emotions once triggered.

Neurotransmitter imbalance – Chemicals like serotonin and dopamine play a crucial role in mood regulation and behaviour. If these neurotransmitters are out of balance, a dog may struggle with anxiety and heightened reactivity.[1]

Gut-brain axis disruptions – The gut and brain are closely linked through the gut-brain axis. Psychological stressors, poor diet, and environmental toxins can disrupt gut bacteria, affecting the production of neurotransmitters that support emotional stability. A key factor in managing dog behaviour and nutrition is supporting gut health through diet. [2,3]

Chronic inflammation – Inflammation, often caused by poor diet, stress, and environmental toxins, can affect brain function, making it harder for dogs to regulate emotions and leading to exaggerated reactivity. This highlights the importance of feeding the best diet for reactive dogs, as the right food choices can help combat inflammation and support emotional stability. [4] “

Why this matters

Understanding reactivity through a physiological lens changes how we approach it. Yes, training and behaviour support are essential—we need strategies to help our dogs navigate their triggers. But if their nervous system is in overdrive, their gut microbiome is imbalanced, and their stress hormones are running high, no amount of training alone will fix the issue.

This is why dog behaviour and nutrition must go hand in hand. By supporting your dog’s internal health, you can lower their baseline stress levels, making it easier for them to process the world and respond to training.

In the next section, we’ll dive deeper into gut health, how food affects dog behaviour, and why what’s in your dog’s bowl could be the key to helping them feel calmer and more in control.

“When everything runs smoothly, the gut microbiome (the collection of bacteria in the digestive system) helps produce key neurotransmitters like serotonin and dopamine—essential for a balanced mood, emotional stability, and focus. But when things go wrong? A disrupted gut microbiome can send the wrong signals to the brain, leading to anxiety, heightened stress responses, and intensified reactivity.”

The science behind food and behaviour

How gut health influences your dog’s behaviour

Your dog’s brain and gut constantly talk to each other—like a 24/7 communication hotline between their stomach and emotions. This connection, known as the gut-brain axis, plays a massive role in your dog’s ability to stay calm, process stress, and regulate emotions.

Dr Katie Woodley explains...

“The connection between your dog’s gut health and behaviour isn’t just anecdotal. It’s backed by science. The gut microbiome plays a crucial role in mood regulation, stress response, and emotional stability, and diet directly impacts this balance.

The gut does far more than digest food—it’s responsible for:

Influencing your dog’s immune system, inflammatory response, and endocrine system, all of which can affect behaviour.
Communicating with the nervous system to control stress responses.
Producing neurotransmitters like serotonin and dopamine, which regulate mood and emotional balance.

When the gut is out of balance (a state called dysbiosis), harmful bacteria outnumber beneficial bacteria, disrupting these processes and making it harder for dogs to handle stress.

Dysbiosis and neurotransmitter production – Beneficial bacteria in the gut help synthesize serotonin and dopamine, essential for mood regulation. When dysbiosis occurs, neurotransmitter production is disrupted, increasing anxiety and emotional instability [5]

Gut-brain communication disruptions – The gut and brain communicate via the vagus nerve and biochemical signaling pathways. A healthy gut microbiome supports clear messaging, while dysbiosis disrupts these signals, heightening stress and reactivity [6].

The role of fiber and prebiotics – The best diet for reactive dogs is rich in fiber and prebiotics that promote the growth of beneficial gut bacteria, helping to maintain a stable microbiome, optimal brain function, and a balanced stress response [2].

If your dog’s gut health is compromised, their ability to regulate emotions will be, too. This can lead to:

More intense reactions to triggers
Longer recovery from stress
Increased anxiety and frustration

The good news? Gut balance can be restored. The right diet can support a healthier microbiome, regulate neurotransmitter production, and help your dog feel more resilient and in control.”

How diet impacts dog reactivity

Dr Katie Woodley continues …

“The food you feed your dog directly affects their behaviour, influencing everything from neurotransmitter production to stress hormone regulation. A poor diet can exacerbate reactivity by causing blood sugar spikes, chronic inflammation, and gut imbalances—all impacting mood and emotional stability.

Many commercial diets contain high levels of processed carbohydrates, inflammatory ingredients, and artificial additives, which can trigger hormonal imbalances, gut dysfunction, and neuroinflammation—leading to increased anxiety and heightened reactivity.

The hidden stressors in processed diets

Carbohydrates & blood sugar spikes – Many kibble diets are packed with over 50% carbohydrates despite dogs having zero physiological need for them. These high-carb diets cause rapid blood sugar spikes, followed by crashes, resulting in mood swings, hyperactivity, and increased anxiety—similar to sugar highs in humans.

Nutrient depletion through processing – High-heat processing in kibble production destroys essential nutrients, including B vitamins, amino acids, and antioxidants, which are critical for brain function and stress regulation. Even if nutrients are added back in, their bioavailability is often reduced, meaning your dog may not absorb what they need for balanced moods.

Leaky gut & chronic inflammation – Processed diets often contain advanced glycation end products (AGEs), contributing to inflammation and increased intestinal permeability (leaky gut). This allows harmful substances to enter the bloodstream, triggering systemic inflammation that can affect brain function and behaviour.

Dysbiosis & gut-brain disruptions – Without enough fiber and prebiotics, beneficial gut bacteria struggle to thrive, leading to microbial imbalances (dysbiosis). A disrupted microbiome reduces serotonin and dopamine production, making it harder for dogs to regulate stress and emotions.

The hormonal impact of poor diets on reactive dogs

Cortisol & chronic stress – A poor diet can elevate cortisol, the body’s primary stress hormone. Chronically high cortisol levels are linked to increased anxiety, over-reactivity, and difficulty settling after triggers.

Insulin & blood sugar regulation – High-carb diets contribute to insulin resistance, which affects blood sugar control and worsens stress responses. Stable insulin levels are essential for maintaining a calm, balanced nervous system.

Adrenal health & stress resilience – The adrenal glands produce cortisol and adrenaline, both of which regulate stress. Nutrients like B vitamins, vitamin C, and omega-3 fatty acids support adrenal function, helping to modulate stress hormone production and improve emotional stability.”

Need help with your dog’s diet?

Contact ProDog’s expert team today for FREE tailored canine nutrition advice

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The best dog food for reactive dogs

A fresh, species-appropriate diet is key to emotional balance. Highly digestible, nutrient-dense ingredients, like those found in a raw dog food diet, support gut health [7], neurotransmitter production, and brain function—helping dogs handle stress better .

The best food for a reactive dog includes:

Minimally processed, species-appropriate ingredients – Quality meat, organs, and bone for essential amino acids.
Nutrient-dense vegetables & herbs – For antioxidants and gut support.
Minimal or no grains, starches, or inflammatory fillers – To prevent gut dysbiosis and blood sugar fluctuations.
Balanced Omega-3s – To reduce neuroinflammation and support brain function.

If you’re new to fresh, natural feeding our Raw Dog Food For Beginners and Top 12 Health Benefits of Raw Feeding Your Dog are great starting points to learn more.

The king of calm: GABA

We can’t talk about nutrition and reactivity without giving a nod to the king of calming—GABA (gamma-aminobutyric acid). This powerful neurotransmitter is like a natural chill pill for the brain, helping to slow things down, reduce overstimulation, and promote relaxation. When GABA levels are low, dogs can become more anxious, reactive and struggle to settle after stressful events.

While GABA itself isn’t something you can add to your dog’s bowl, the right species-appropriate diet provides all the building blocks needed to support natural GABA production. Key nutrients like L-glutamine, magnesium, and taurine, found in meat, organ meats, bone broth, and fermented foods, help keep GABA levels in check.

A healthy gut microbiome also plays a significant role since beneficial gut bacteria influence neurotransmitter balance, including GABA regulation.

Supplements that support a reactive dog

While a minimally processed, natural diet, such as complete raw dog food, lays the foundation for emotional balance, targeted supplementation can provide extra support for reactive dogs—helping to strengthen the gut, regulate inflammation, and support the nervous system.

Dr Katie Woodley’s top picks :

“There’s no one-size-fits-all approach, but the following supplements and herbs have been shown to aid stress regulation and help reactive dogs feel more resilient.

Gut health & microbiome support

A healthy gut is the key to balanced behaviour, as it influences neurotransmitter production, inflammation control, and stress resilience. These supplements help restore gut balance and improve digestion:

Probiotics & Prebiotics — Promote a healthy microbiome, supporting the gut-brain axis and neurotransmitter production.

Colostrum for Dogs – Contains growth factors and immunoglobulins that restore gut integrity and balance brain chemistry.

Bone Broth – Rich in collagen and amino acids, it helps repair the gut lining and regulate inflammation.

Slippery Elm – A natural gut soother, it calms the digestive system and supports nutrient absorption.

Anti-inflammatory support

Chronic inflammation, whether from diet, stress, or environmental factors, can heighten reactivity. These ingredients help lower inflammation and support brain function:

Omega-3 Fish Oil – EPA and DHA reduce neuroinflammation, supporting a calmer nervous system.

Turmeric (with Black Pepper) is a natural anti-inflammatory powerhouse that aids brain and gut health.

Medicinal Mushrooms – Such as reishi and lion’s mane, which support cognitive function and stress resilience.

Nervous system & stress regulation

These supplements help regulate the nervous system, making it easier for dogs to process stress and recover from triggers:

Chamomile – Known for its calming properties, chamomile can help ease anxiety and digestive discomfort.

Lemon Balm – Supports mood regulation and reduces nervous tension.

Ashwagandha – An adaptogen that helps lower cortisol levels and improves stress resilience. [9,10] Other adaptogens include: Astragalus, Ginseng, Reish mushrooms

Valerian – A natural sedative herb known to promote deep relaxation and reduce anxiety-related tension.

Rolled oats – A well-known nervine, oats help strengthen the nervous system, regulate stress responses, and promote emotional resilience.

These lists are not exhaustive, and each dog’s individual needs should be considered when choosing supplements.”

Ready-made dog supplements

If you’d prefer expertly formulated blends specifically designed for dog health, ProDog’s range of supplements for dogs offer targeted support for gut health, stress relief, and overall well-being—key factors in helping reactive dogs thrive.

Colostrum is packed with immunoglobulins, growth factors, and peptides that restore gut balance, support brain chemistry, and regulate inflammation—key for cognitive function and emotional stability.

Supports gut integrity and immune health
Promotes neurotransmitter balance

For more on colostrum’s benefits, check out 10 Benefits of Colostrum Supplement for Dogs.

Digest

As gut health and reactivity are closely linked, ProDog’s Digest, dog gut health supplement, provides powerful whole-food ingredients that soothe and strengthen the digestive system.

🔹 Contains chamomile, slippery elm, aloe vera, and liquorice root to ease digestive discomfort.

🔹 Supports optimal gut microbiome function.

Check out our article, Dog Poo: Unveiling the Clues Into Canine Health, to see if your dog’s digestion needs extra support.

Boost

Packed with essential vitamins, minerals, antioxidants, and plant proteins, Boost, a dog multivitamin and mineral supplement, is designed to counteract oxidative stress, support immune health, and promote gut balance—key areas that affect reactivity and stress resilience.

🔹 Probiotics for microbiome support.

🔹 Antioxidants to combat oxidative stress from anxiety and overstimulation.

Muscle+

Many reactive dogs struggle with maintaining an ideal weight, and Muscle+, a weight gain supplement for dogs, provides targeted nutritional support for healthy weight gain and nervous system nourishment.

🔹 Contains fish collagen, omega-rich oils, and pumpkin seed powder to support gut and brain health.

🔹 Includes L-Taurine and L-Glutamine, amino acids that aid nervous system function and stress recovery.

🔹 Rolled oat powder helps soothe and balance the nervous system

For dogs that struggle with chronic stress, anxiety, or reactivity, supplementation can help bridge the gap between diet and behavioural support—providing the biochemical foundation needed for a calmer, more resilient dog.

If you’re new to dog supplements, ProDog’s Beginner’s Guide to Dog Supplements is the perfect starting point to learn more.

Reactive dog nutrition

Living with a reactive dog can feel overwhelming, but when you take a step back and look at the bigger picture—beyond just training—you’ll see there are many other pieces to the puzzle that can make a difference.

There have been so many learning moments with Rudi. Some days, it’s smooth sailing; other days, it’s like living with an emotional tornado. But thanks to the right nutrition, a better understanding of his triggers, and guidance from professionals like Dr Katie Woodley, insightful trainers and behaviourist support, we now have far more smooth sailing days than choppy waters.

Remember, it’s not just about what’s happening inside your dog. It’s also about the energy you bring to the table. Dogs are incredibly intuitive; they pick up on our emotions more than we realise. When we’re calm and steady, our dogs feel safer. When we’re stressed or impatient, they absorb that too. Becoming aware of how your own mindset impacts your dog’s emotional state can make a world of difference in how they process stress.

By fuelling your dog’s body with the right nutrients, supporting their gut-brain connection, and being mindful of your own energy, you create an environment where they can feel calmer, safer, and more confident. Combine this with patience, training, understanding their innate needs, and relationship building, and you’ll start seeing real, lasting changes—both in them and yourself.

If you’re unsure where to start with your dog’s diet, ProDog’s expert nutrition team is here to help. We offer FREE tailored nutrition advice to support your dog’s health and behaviour. Contact us today to get expert recommendations for your dog’s specific needs.

For more in-depth guidance on holistic health, visit Dr Katie Woodley’s website, The Natural Pet Doctor, where she shares expert veterinary insights on supporting your dog naturally.

Reactive Dog Nutrition FAQs

Can food make my dog reactive?

Yes, diet plays a significant role in dog behaviour and reactivity. Highly processed, carbohydrate-heavy diets can cause:

Blood sugar spikes, leading to hyperactivity and crashes.
Gut imbalances that reduce serotonin and dopamine production.
Increased inflammation, affecting brain function and emotional stability.

On the other hand, a natural, species-appropriate diet, such as a raw dog food diet, supports balanced neurotransmitter production, gut health, and a calmer nervous system. Learn more in the blog above, especially in the ‘How diet impacts reactivity’ section.

What nutrients help calm a reactive dog?

Key nutrients that support emotional balance and stress resilience include:

Omega-3 fatty acids – Reduce neuroinflammation and support brain health.
L-Tryptophan – A precursor to serotonin, promoting relaxation.
Magnesium & Zinc – Essential for nervous system stability.
Probiotics & Prebiotics – Support gut health and neurotransmitter production.
Adaptogenic herbs – Such as ashwagandha, chamomile, valerian, and lemon balm help regulate stress hormones.

For a deeper dive into nutrients and foods that support reactive dogs, check out the blog above and go straight to the section, ‘Supplements that support a reactive dog’.

How to calm a reactive dog naturally through diet?

Switching to a species-appropriate diet such as raw or minimaly processed foods, is one of the best ways to naturally support calm, balanced behaviour. A diet rich in:

High-quality raw animal proteins (muscle meat, organs, bone).
Healthy fats (omega-3-rich fish, raw-fed animal fats).
Prebiotic fibre (small amounts of nutrient-dense vegetables).

A reputable raw dog food supplier removes the guesswork from raw feeding. A high-quality, complete raw diet provides balanced nutrition for your dog and is simple to serve.

If your dog is already raw-fed, targeted supplementation can further support gut health and nervous system balance. Check out ‘Supplements that support a reactive dog’ in the blog above.

What is the best diet for reactive dogs?

The best diet for reactive dogs is one that is:

High in protein and healthy fats to support stable energy levels.
Anti-inflammatory, avoiding processed grains, starches, and fillers.
Rich in essential fatty acids to support brain and nervous system function.

A balanced raw dog food diet meets all these needs and supports gut health, brain chemistry, and emotional resilience. Learn more in the blog above.

Why does my dog's diet affect their behaviour?

Your dog’s gut, nervous system, and brain are all connected. A poor diet can lead to:

Gut microbiome imbalances, reducing serotonin and dopamine production.
Chronic inflammation, increasing stress and reactivity.
Blood sugar spikes and crashes, causing mood swings and anxiety.

A fresh, whole-food diet supports better nutrient absorption, brain function, and overall emotional balance. Read more in the blog above. The section ‘How diet impacts reactivity’ gives a deeper insight.

How do probiotics help reactive dogs?

Probiotics support a healthy gut microbiome, which plays a key role in:

1. Neurotransmitter production – Gut bacteria help create serotonin and dopamine, which regulate mood.

2. Reducing inflammation – A balanced microbiome lowers gut and brain inflammation, reducing stress responses.

3. Regulating the gut-brain axis – Supporting emotional stability and stress resilience.

What role does the gut play in dog behaviour?

The gut-brain axis is a direct link between the gut and the brain. When the gut is healthy, it helps produce mood-regulating neurotransmitters like serotonin and GABA, keeping stress responses in check.

If gut health is compromised (due to poor diet, stress, or dysbiosis), it can contribute to:

Increased anxiety and reactivity.
Difficulty coping with stress.
Poor digestion, leading to further health issues.

Learn more in the blog above. The section ‘The science behind food and behaviour’ is a deeper dive.

Can a raw diet help dog anxiety?

Yes. A balanced, raw diet supports stable energy, gut health, and brain function, all of which help manage anxiety and reactivity.

Dogs on a processed diet may struggle with:

Inflammatory ingredients that trigger oxidative stress and nervous system dysregulation.
Blood sugar imbalances that cause unpredictable mood swings.
Gut dysbiosis that reduces serotonin production.

Switching to fresh, whole foods gives your dog the nutrients needed to feel calmer and more resilient. Read more in the blog above, and hop straight to the section, ‘Best dog food for reactive dogs’.

Should I consult a veterinarian or a behaviourist for dietary advice for my reactive dog?

For diet-related behaviour concerns, a canine nutritionist or holistic vet can help assess your dog’s nutritional needs. A behaviourist can support training and management, while a vet can rule out any underlying medical issues affecting behaviour.

ProDog’s nutritionist team offers free nutrition advice to help you find the best diet for your dog’s needs.

Are there any natural remedies or herbs that can help calm a reactive dog's nervous system?

Yes. Many natural ingredients and herbs support stress regulation, including:

Chamomile and lemon balm – Help ease nervous tension.
Ashwagandha and valerian – Support adrenal balance and relaxation.
Rolled oats – Natural nervine that helps strengthen the nervous system.
Omega-3s and turmeric – Reduce neuroinflammation and support brain function.

For a full breakdown, check out ‘Supplements that support a reactive dog’ in the blog above.

References

Mondo E, Barone M, Soverini M, D’Amico F, Cocchi M, Petrulli C, Mattioli M, Marliani G, Candela M, Accorsi PA. 2020 Jan. Gut microbiome structure and adrenocortical activity in dogs with aggressive and phobic behavioral disorders. Heliyon. 29;6(1):e03311. Doi: 10.1016/j.heliyon.2020.e03311.
Bercik, P et al. 2011. “The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication.” Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society vol. 23,12 : 1132-9. doi:10.1111/j.1365-2982.2011.01796.x
Wood, J. Mar 2018. Chapter 15 – Enteric Nervous System: Brain-in-the-Gut. Physiology of the Gastrointestinal Tract;, 6:361-372. Doi: 10.1016/B978-0-12-809954-4.00015-3
Candellone, Alessia et al. June 2022.“Changes in the Oxidative Stress Status of Dogs Affected by Acute Enteropathies.” Veterinary sciences vol. 9,6 276. Doi:10.3390/vetsci9060276
Kubinyi E, Bel Rhali S, Sándor S, Szabó A, Felföldi T. Aug 2020. Gut Microbiome Composition is Associated with Age and Memory Performance in Pet Dogs. Animals (Basel). ;10(9):1488. Doi: 10.3390/ani10091488.
KirchoffNS, Udell MAR, Sharpton. 2019. The gut microbiome correlates with cospecific aggression in a small population of rescued dogs (Canin Familiaris). PeerJ. DOI: 10.7717/peerj.6103
Sandri, M., Dal Monego, S., Conte, G., Sgorlon, S., Stefanon, B. Feb 2017. Raw meat based diet influences faecal microbiome and end products of fermentation in healthy dogs. BMC Veterinary Research;, 13(65). Doi: 10.1186/s12917-017-0981-z
Jenkins, T., Nguyen, J., Polglaze, K., Bertrand. P. Jan 2016. Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis. Nutrients;, 8(1):56. Doi: 10.3390/nu8010056
Panossian, Alexander, and Georg Wikman. Jan. 2010. “Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress-Protective Activity.” Pharmaceuticals (Basel, Switzerland) vol. 3,1 188-224. 19, Doi:10.3390/ph3010188
Panossian, Alexander G et al. 2021. “Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases.” Medicinal Research Reviews vol. 41,1 : 630-703. Doi:10.1002/med.21743