Vaccination is a process that vets and doctors use to trick the body into producing protective immune responses against infection.
It’s a phenomenon that’s been known about for hundreds of years, but the English doctor Edward Jenner in the 1790s made the process famous. Let’s use his experiments to help us understand the workings of vaccination.
Jenner noticed that milkmaids and people working with cattle who had contracted cowpox did not become infected, noticeably, by the much more deadly smallpox virus. He had been alerted to this phenomenon from accounts of manipulating infection in other parts of the world, for example, Turkey and China.
He did an experiment in 1796 whereby he gave cowpox to a young boy, James Phipps, to see if it would protect him from subsequent infection with smallpox. It was a risky experiment to young James, but it paid off.
The boy was first inoculated with cowpox, and then a few weeks later was given a dose of smallpox that would typically have caused severe disease, if not death. The boy survived, and so began the dawn of vaccination in the western world. Interestingly, the word vaccination comes from the cowpox virus, which is called ‘vaccinia virus’, from the Latin ‘vacca’ for cow.
Jenner’s experiment demonstrates you can protect against infectious disease and not have to go through the risk of being infected with dangerous bugs to generate effective immunity.
Vaccination is now standard throughout the western world and has arguably saved millions of human and animal lives.
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